Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates

Overview

Information

Number: 6743225
Application: 09/818206
Filing date: 03/27/2001
Issue date: 06/01/2004
Inventor(s): Javier E. Sanchez, Jeffrey A. Hall, Michael E. Benser, Raymond E. Ideker, William M. Smith

US Classification: 128/898; 606/32; 606/34; 606/41; 606/51; 607/101; 607/105

Citations

Cardiac Pacemakers (25)

Number	Title	Issue Date
6042580	Electrode having composition-matched, common-lead thermocouple wire for providing multiple temperature-sensitive junctions	2000/03/28
6042580	Electrode having composition-matched, common-lead thermocouple wire for providing multiple temperature-sensitive junctions	2000/03/28
5364352	Catheter for electrophysiological procedures	1994/11/15
6146381	Catheter having distal region for deflecting axial forces	2000/11/14
6099524	Electrophysiological mapping and ablation catheter and method	2000/08/08
6099524	Electrophysiological mapping and ablation catheter and method	2000/08/08
5492119	Catheter tip stabilizing apparatus	1996/02/20
6059778	RF ablation apparatus and method using unipolar and bipolar techniques	2000/05/09
6059778	RF ablation apparatus and method using unipolar and bipolar techniques	2000/05/09
6050994	RF ablation apparatus and method using controllable duty cycle with alternate phasing	2000/04/18
6050994	RF ablation apparatus and method using controllable duty cycle with alternate phasing	2000/04/18
6049737	Catheter having common lead for electrode and sensor	2000/04/11
6045550	Electrode having non-joined thermocouple for providing multiple temperature-sensitive junctions	2000/04/04
6045550	Electrode having non-joined thermocouple for providing multiple temperature-sensitive junctions	2000/04/04
5596995	Biomedical device having a temperature sensing system	1997/01/28
5971980	System for controlling the energy delivered to a patient for ablation	1999/10/26
5857997	Catheter for electrophysiological procedures	1999/01/12
5810740	System and method for analyzing electrogram waveforms	1998/09/22
5741320	Catheter control system having a pulley	1998/04/21
5735280	Ultrasound energy delivery system and method	1998/04/07
5681280	Catheter control system	1997/10/28
5666970	Locking mechanism for catheters	1997/09/16
5662606	Catheter for electrophysiological procedures	1997/09/02
5617854	Shaped catheter device and method	1997/04/08
5606974	Catheter having ultrasonic device	1997/03/04

Edwards Lifesciences (2)

Number	Title	Issue Date
5452733	Methods for performing thoracoscopic coronary artery bypass	1995/09/26
5571215	Devices and methods for intracardiac procedures	1996/11/05

Engineering & Research Associates (1)

Number	Title	Issue Date
6113592	Apparatus and method for controlling ablation depth	2000/09/05

St. Jude Medical (1)

Number	Title	Issue Date
6161543	Methods of epicardial ablation for creating a lesion around the pulmonary veins	2000/12/19

AtriCure (1)

Number	Title	Issue Date
6546935	Method for transmural ablation	2003/04/15

Boston Scientific (1)

Number	Title	Issue Date
6071281	Surgical method and apparatus for positioning a diagnostic or therapeutic element within the body and remote power control unit for use with same	2000/06/06

BioSense (1)

Number	Title	Issue Date
5954665	Cardiac ablation catheter using correlation measure	1999/09/21

Heartport (1)

Number	Title	Issue Date
5797960	Method and apparatus for thoracoscopic intracardiac procedures	1998/08/25

Abstract

Abstract

Methods, systems, and computer program products measure electrical activity of the cardiac tissue proximate the lesion site during an ablation treatment, and then compare the measurements to determine whether the lesion is clinically efficacious so as to be able to block myocardial propagation. The methods can include obtaining the measurements and performing the ablation therapy while the subject is experiencing atrial fibrillation and may measure the standard deviation of the electrogram signal.

Assignees with Similar Patents

The Johns Hopkins University (6)

Number	Title
7155271	System and method for magnetic-resonance-guided electrophysiologic and ablation procedures
100471465	System and method for magnetic-resonance-guided electrophysiologic and ablation procedures
7412276	Brain therapy
101704343	MRI-GUIDED THERAPY METHODS AND RELATED SYSTEMS
6701176	Magnetic-resonance-guided imaging, electrophysiology, and ablation
102042630	System and method for magnetic-resonance-guided electrophysiologic and ablation procedures

St. Jude Medical (6)

Number	Title
8364253	System and method for mapping electrophysiology information onto complex geometry
101386657	System and Method for Three Dimensional Mapping of Electrophysiology Information
102295770	System and Method for Assessing Coupling Between an Electrode and Tissue
7774051	System and method for mapping electrophysiology information onto complex geometry
7819862	Method for arrhythmias treatment based on spectral mapping during sinus rhythm
6811562	Procedures for photodynamic cardiac ablation therapy and devices for those procedures

PaceSetter (4)

Number	Title
7308308	Method to monitor progression of atrial fibrillation and to detect its susceptibility for termination
7783352	Optimizing anti-tachycardia pacing for terminating atrial fibrillation
6431173	Method of using electrical energy to produce temporary conduction block for defibrillation and cardioversion
102612207	OPTIMIZING ANTI-TACHYCARDIA PACING FOR TERMINATING ATRIAL FIBRILLATION

Siemens (4)

Number	Title
103010392	Signal Analysis System for Heart Condition Determination
103386923	System for Automatic Medical Ablation Control
101893792	Method and System for Atrial Fibrillation Analysis, Characterization, and Mapping
102113465	EP SIGNAL MAPPING-BASED OPTICAL ABLATION FOR PATIENT MONITORING AND MEDICAL APPLICATIONS

Medtronic (4)

Number	Title
102452798	Irrigated Ablation Catheter System and Methods
102238393	Tissue Lesion Evaluation
7311705	Catheter apparatus for treatment of heart arrhythmia
5193550	Method and apparatus for discriminating among normal and pathological tachyarrhythmias

Referenced by

Covidien (103)

Number	Title	Issue Date
7645142	Electrical receptacle assembly	2010/01/12
7651492	Arc based adaptive control system for an electrosurgical unit	2010/01/26
7651492	Arc based adaptive control system for an electrosurgical unit	2010/01/26
7766693	Connector systems for electrosurgical generator	2010/08/03
7766693	Connector systems for electrosurgical generator	2010/08/03
7834484	Connection cable and method for activating a voltage-controlled generator	2010/11/16
7901400	Method and system for controlling output of RF medical generator	2011/03/08
7901400	Method and system for controlling output of RF medical generator	2011/03/08
7927328	System and method for closed loop monitoring of monopolar electrosurgical apparatus	2011/04/19
7927328	System and method for closed loop monitoring of monopolar electrosurgical apparatus	2011/04/19
7947039	Laparoscopic apparatus for performing electrosurgical procedures	2011/05/24
7947039	Laparoscopic apparatus for performing electrosurgical procedures	2011/05/24
7972328	System and method for tissue sealing	2011/07/05
7972328	System and method for tissue sealing	2011/07/05
7972332	System and method for controlling electrosurgical snares	2011/07/05
8004121	Connection cable and method for activating a voltage-controlled generator	2011/08/23
8025660	Universal foot switch contact port	2011/09/27
8080008	Method and system for programming and controlling an electrosurgical generator system	2011/12/20
8080008	Method and system for programming and controlling an electrosurgical generator system	2011/12/20
8096961	Switched resonant ultrasonic power amplifier system	2012/01/17
8096961	Switched resonant ultrasonic power amplifier system	2012/01/17
8105323	Method and system for controlling output of RF medical generator	2012/01/31
8105323	Method and system for controlling output of RF medical generator	2012/01/31
8113057	Switched resonant ultrasonic power amplifier system	2012/02/14
8113057	Switched resonant ultrasonic power amplifier system	2012/02/14
8147485	System and method for tissue sealing	2012/04/03
8152800	Electrosurgical systems and printed circuit boards for use therewith	2012/04/10
8174267	Intermittent microwave energy delivery system	2012/05/08
8180433	Microwave system calibration apparatus, system and method of use	2012/05/15
8187262	Dual synchro-resonant electrosurgical apparatus with bi-directional magnetic coupling	2012/05/29
8202271	Dual synchro-resonant electrosurgical apparatus with bi-directional magnetic coupling	2012/06/19
8202271	Dual synchro-resonant electrosurgical apparatus with bi-directional magnetic coupling	2012/06/19
8216220	System and method for transmission of combined data stream	2012/07/10
8216223	System and method for tissue sealing	2012/07/10
8226639	System and method for output control of electrosurgical generator	2012/07/24
8231616	Transformer for RF voltage sensing	2012/07/31
8231616	Transformer for RF voltage sensing	2012/07/31
8241278	Laparoscopic apparatus for performing electrosurgical procedures	2012/08/14
8241278	Laparoscopic apparatus for performing electrosurgical procedures	2012/08/14
8242782	Microwave ablation generator control system	2012/08/14
8248075	System, apparatus and method for dissipating standing wave in a microwave delivery system	2012/08/21
8267928	System and method for closed loop monitoring of monopolar electrosurgical apparatus	2012/09/18
8267928	System and method for closed loop monitoring of monopolar electrosurgical apparatus	2012/09/18
8267929	Method and system for programming and controlling an electrosurgical generator system	2012/09/18
8267929	Method and system for programming and controlling an electrosurgical generator system	2012/09/18
8287527	Microwave system calibration apparatus and method of use	2012/10/16
8287528	Vessel sealing system	2012/10/16
8287528	Vessel sealing system	2012/10/16
8298223	Method and system for programming and controlling an electrosurgical generator system	2012/10/30
8298223	Method and system for programming and controlling an electrosurgical generator system	2012/10/30
8303580	Method and system for programming and controlling an electrosurgical generator system	2012/11/06
8303580	Method and system for programming and controlling an electrosurgical generator system	2012/11/06
8346370	Delivered energy generator for microwave ablation	2013/01/01
8353905	System and method for transmission of combined data stream	2013/01/15
8403924	Shielding for an isolation apparatus used in a microwave generator	2013/03/26
8475447	System and method for closed loop monitoring of monopolar electrosurgical apparatus	2013/07/02
8475447	System and method for closed loop monitoring of monopolar electrosurgical apparatus	2013/07/02
8485993	Switched resonant ultrasonic power amplifier system	2013/07/16
8485993	Switched resonant ultrasonic power amplifier system	2013/07/16
8486061	Imaginary impedance process monitoring and intelligent shut-off	2013/07/16
8512332	Real-time arc control in electrosurgical generators	2013/08/20
8523855	Circuit for controlling arc energy from an electrosurgical generator	2013/09/03
8523855	Circuit for controlling arc energy from an electrosurgical generator	2013/09/03
8542019	Microwave ablation generator control system	2013/09/24
8556890	Arc based adaptive control system for an electrosurgical unit	2013/10/15
8647340	Thermocouple measurement system	2014/02/11
8647340	Thermocouple measurement system	2014/02/11
8663214	Method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm	2014/03/04
8663214	Method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm	2014/03/04
8685015	System and method for multi-pole phase-shifted radio frequency application	2014/04/01
8685016	System and method for tissue sealing	2014/04/01
8734438	Circuit and method for reducing stored energy in an electrosurgical generator	2014/05/27
8734438	Circuit and method for reducing stored energy in an electrosurgical generator	2014/05/27
8747398	Frequency tuning in a microwave electrosurgical system	2014/06/10
8777941	Adjustable impedance electrosurgical electrodes	2014/07/15
8797039	Microwave ablation generator control system	2014/08/05
8966981	Switched resonant ultrasonic power amplifier system	2015/03/03
8966981	Switched resonant ultrasonic power amplifier system	2015/03/03
9113900	Method and system for controlling output of RF medical generator	2015/08/25
9119624	ARC based adaptive control system for an electrosurgical unit	2015/09/01
9168089	Method and system for controlling output of RF medical generator	2015/10/27
9186200	System and method for tissue sealing	2015/11/17
9190704	Electrosurgical systems and printed circuit boards for use therewith	2015/11/17
9254172	Shielding for an isolation apparatus used in a microwave generator	2016/02/09
9271790	Real-time arc control in electrosurgical generators	2016/03/01
9474564	Method and system for compensating for external impedance of an energy carrying component when controlling an electrosurgical generator	2016/10/25
9474564	Method and system for compensating for external impedance of an energy carrying component when controlling an electrosurgical generator	2016/10/25
9498285	Impedance matching in a microwave electrosurgical system	2016/11/22
9522032	Circuit and method for reducing stored energy in an electrosurgical generator	2016/12/20
9522032	Circuit and method for reducing stored energy in an electrosurgical generator	2016/12/20
9526576	Microwave ablation generator control system	2016/12/27
9636165	Systems and methods for measuring tissue impedance through an electrosurgical cable	2017/05/02
9642665	Method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm	2017/05/09
9655670	Systems and methods for measuring tissue impedance through an electrosurgical cable	2017/05/23
9768373	Switched resonant ultrasonic power amplifier system	2017/09/19
9861424	Measurement and control systems and methods for electrosurgical procedures	2018/01/09
9872719	Systems and methods for generating electrosurgical energy using a multistage power converter	2018/01/23
10070922	Microwave ablation generator control system	2018/09/11
10582964	Method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm	2020/03/10
10743935	Microwave ablation generator control system	2020/08/18
11013548	Method and system for compensating for external impedance of energy carrying component when controlling electrosurgical generator	2021/05/25
11135001	Systems and methods for generating electrosurgical energy using a multistage power converter	2021/10/05
12226143	Universal surgical footswitch toggling	2025/02/18

farapulse (29)

Number	Title	Issue Date
9987081	Systems, devices, and methods for signal generation	2018/06/05
9999465	Method and apparatus for rapid and safe pulmonary vein cardiac ablation	2018/06/19
10130423	Systems, devices, and methods for focal ablation	2018/11/20
10172673	Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue	2019/01/08
10322286	Systems, apparatuses and methods for delivery of ablative energy to tissue	2019/06/18
10433906	Method and apparatus for rapid and selective transurethral tissue ablation	2019/10/08
10433908	Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue	2019/10/08
10507302	Systems, apparatuses, and methods for guide wire delivery	2019/12/17
10512505	Systems, apparatuses and methods for delivery of ablative energy to tissue	2019/12/24
10512779	Systems, apparatuses and methods for delivery of ablative energy to tissue	2019/12/24
10517672	Apparatus and methods for renal denervation ablation	2019/12/31
10617467	Systems, devices, and methods for focal ablation	2020/04/14
10617867	Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue	2020/04/14
10624693	Method and apparatus for rapid and selective tissue ablation with cooling	2020/04/21
10625080	Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation	2020/04/21
10660702	Systems, devices, and methods for focal ablation	2020/05/26
10687892	Systems, apparatuses, and methods for delivery of pulsed electric field ablative energy to endocardial tissue	2020/06/23
10688305	Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation	2020/06/23
10709502	Systems, apparatuses and methods for delivery of ablative energy to tissue	2020/07/14
10709891	Systems, apparatuses and methods for delivery of ablative energy to tissue	2020/07/14
10835314	Method and apparatus for rapid and safe pulmonary vein cardiac ablation	2020/11/17
10842561	Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue	2020/11/24
10842572	Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines	2020/11/24
10893905	Systems, apparatuses, and methods for ventricular focal ablation	2021/01/19
11020179	Systems, devices, and methods for focal ablation	2021/06/01
11020180	Epicardial ablation catheter	2021/06/01
11033236	Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation	2021/06/15
11065047	Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses	2021/07/20
11259869	Methods and apparatus for selective tissue ablation	2022/03/01

epix therapeutics (25)

Number	Title	Issue Date
9510905	Systems and methods for high-resolution mapping of tissue	2016/12/06
9517103	Medical instruments with multiple temperature sensors	2016/12/13
9522036	Ablation devices, systems and methods of using a high-resolution electrode assembly	2016/12/20
9522037	Treatment adjustment based on temperatures from multiple temperature sensors	2016/12/20
9592092	Orientation determination based on temperature measurements	2017/03/14
9636164	Contact sensing systems and methods	2017/05/02
9993178	Methods of determining catheter orientation	2018/06/12
10166062	High-resolution mapping of tissue with pacing	2019/01/01
10231779	Ablation catheter with high-resolution electrode assembly	2019/03/19
10383686	Ablation systems with multiple temperature sensors	2019/08/20
10413212	Methods and systems for enhanced mapping of tissue	2019/09/17
10499983	Ablation systems and methods using heat shunt networks	2019/12/10
10660701	Methods of removing heat from an electrode using thermal shunting	2020/05/26
10675081	Contact sensing systems and methods	2020/06/09
10888373	Contact assessment between an ablation catheter and tissue	2021/01/12
10893903	Medical instruments having contact assessment features	2021/01/19
11135009	Electrode assembly with thermal shunt member	2021/10/05
11179197	Methods of determining catheter orientation	2021/11/23
11389230	Systems for determining catheter orientation	2022/07/19
11534227	High-resolution mapping of tissue with pacing	2022/12/27
11576714	Contact sensing systems and methods	2023/02/14
11617618	Contact assessment between an ablation catheter and tissue	2023/04/04
11642167	Electrode assembly with thermal shunt member	2023/05/09
11701171	Methods of removing heat from an electrode using thermal shunting	2023/07/18
12121291	Methods of determining catheter orientation	2024/10/22

Boston Scientific (25)

Number	Title	Issue Date
8951247	Methods and apparatus for forming cardiac lesions and assessing lesion quality	2015/02/10
11241282	Method and apparatus for rapid and selective transurethral tissue ablation	2022/02/08
11357978	Systems, devices, and methods for signal generation	2022/06/14
11497541	Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses	2022/11/15
11589919	Apparatus and methods for renal denervation ablation	2023/02/28
11589921	Systems, apparatuses and methods for delivery of ablative energy to tissue	2023/02/28
11622803	Method and apparatus for rapid and selective tissue ablation with cooling	2023/04/11
11684408	Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses	2023/06/27
11738200	Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation	2023/08/29
11833350	Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue	2023/12/05
11931090	Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses	2024/03/19
12042208	Systems, devices, and methods for ablation using surgical clamps	2024/07/23
12121720	Systems, devices, and methods for signal generation	2024/10/22
12137968	Methods and apparatus for multi-catheter tissue ablation	2024/11/12
12144541	Systems, apparatuses and methods for delivery of ablative energy to tissue	2024/11/19
12150698	Systems, apparatuses, and methods for ventricular focal ablation	2024/11/26
12161397	Method and apparatus for rapid and selective transurethral tissue ablation	2024/12/10
12246143	Systems, apparatuses, and methods for guide wire delivery	2025/03/11
12257080	Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation	2025/03/25
12268437	Electric field application for single shot cardiac ablation by irreversible electroporation	2025/04/08
12274491	Epicardial ablation catheter	2025/04/15
12295637	Method and apparatus for controlled delivery of pulsed electric field ablative energy to tissue	2025/05/13
12295648	Method and apparatus for rapid and safe pulmonary vein cardiac ablation	2025/05/13
12310652	Hybrid electroporation ablation catheter	2025/05/27
12318130	Systems, apparatuses, and methods for delivery of pulsed electric field ablative energy to endocardial tissue	2025/06/03

Medtronic (17)

Number	Title	Issue Date
7740627	Surgical method and apparatus for treating atrial fibrillation	2010/06/22
7850685	Ablation catheter	2010/12/14
8273084	Atrial ablation catheter and method of use	2012/09/25
8337492	Ablation catheter	2012/12/25
8486063	Ablation catheter	2013/07/16
8617152	Ablation system with feedback	2013/12/31
8771269	RF energy delivery system and method	2014/07/08
8834461	Low power tissue ablation system	2014/09/16
8845631	Systems and methods of performing medical procedures	2014/09/30
8926602	Triple balloon catheter	2015/01/06
8979841	Ablation catheter	2015/03/17
9566113	Low power tissue ablation system	2017/02/14
9642675	Ablation catheter	2017/05/09
9743973	Triple balloon catheter	2017/08/29
9867661	Systems and methods of performing medical procedures	2018/01/16
10219857	RF energy delivery system	2019/03/05
10881456	Systems and methods of performing medical procedures	2021/01/05

St. Jude Medical (17)

Number	Title	Issue Date
8603084	System and method for assessing the formation of a lesion in tissue	2013/12/10
8998890	Assessment of electrode coupling for tissue ablation	2015/04/07
9173586	System and method for assessing coupling between an electrode and tissue	2015/11/03
9204927	System and method for presenting information representative of lesion formation in tissue during an ablation procedure	2015/12/08
9254163	Assessment of electrode coupling for tissue ablation	2016/02/09
9271782	Assessment of electrode coupling of tissue ablation	2016/03/01
9283025	Assessment of electrode coupling for tissue ablation	2016/03/15
9283026	Assessment of electrode coupling for tissue ablation	2016/03/15
9339325	System and method for assessing lesions in tissue	2016/05/17
9492226	Graphical user interface for real-time RF lesion depth display	2016/11/15
9610119	System and method for assessing the formation of a lesion in tissue	2017/04/04
10182860	Assessment of electrode coupling for tissue ablation	2019/01/22
10201388	Graphical user interface for real-time RF lesion depth display	2019/02/12
10362959	System and method for assessing the proximity of an electrode to tissue in a body	2019/07/30
10555685	Method and apparatus for determining tissue morphology based on phase angle	2020/02/11
10675086	System and method for presenting information representative of lesion formation in tissue during an ablation procedure	2020/06/09
11517372	System and method for assessing lesions in tissue	2022/12/06

460MEDICAL, INC. (10)

Number	Title	Issue Date
10716462	Systems and methods for visualizing ablated tissue	2020/07/21
10722301	Systems and methods for lesion assessment	2020/07/28
11559192	Systems and methods for visualizing ablated tissue	2023/01/24
11559352	Systems and methods for lesion assessment	2023/01/24
12075980	Systems and methods for visualizing ablated tissue	2024/09/03
10682179	Systems and methods for determining tissue type	2020/06/16
10779904	Systems and methods for lesion formation and assessment	2020/09/22
11596472	Systems and methods for assessment of contact quality	2023/03/07
12076081	Systems and methods for optical interrogation of ablation lesions	2024/09/03
12295795	Systems and methods for lesion formation and assessment	2025/05/13

ENDOPHOTONIX (8)

Number	Title	Issue Date
7137977	Atraumatic laser tip for atrial fibrillation treatment	2006/11/21
7163534	Laser-based maze procedure for atrial fibrillation	2007/01/16
7169142	Malleable energy wand for maze procedure	2007/01/30
7232437	Assessment of lesion transmurality	2007/06/19
7238179	Apparatus and method for guided ablation treatment	2007/07/03
7238180	Guided ablation with end-fire fiber	2007/07/03
7267674	Apparatus and method for laser treatment	2007/09/11
7338485	Cardiac lesions with continuity testing	2008/03/04

George Washington University (8)

Number	Title	Issue Date
10076238	Systems and methods for visualizing ablated tissue	2018/09/18
10716462	Systems and methods for visualizing ablated tissue	2020/07/21
10722301	Systems and methods for lesion assessment	2020/07/28
10736512	Systems and methods for visualizing ablated tissue	2020/08/11
11457817	Systems and methods for hyperspectral analysis of cardiac tissue	2022/10/04
11559192	Systems and methods for visualizing ablated tissue	2023/01/24
11559352	Systems and methods for lesion assessment	2023/01/24
12075980	Systems and methods for visualizing ablated tissue	2024/09/03

Maquet Cardiovascular, (5)

Number	Title	Issue Date
7099717	Catheter having improved steering	2006/08/29
7192427	Apparatus and method for assessing transmurality of a tissue ablation	2007/03/20
7303560	Method of positioning a medical instrument	2007/12/04
7346399	Monopole tip for ablation catheter	2008/03/18
7497858	Apparatus and method for assessing transmurality of a tissue ablation	2009/03/03

Mayo Foundation for Medical Education and Research (5)

Number	Title	Issue Date
9144431	Enhanced signal navigation and capture systems and methods	2015/09/29
9198683	Tissue capture and occlusion systems and methods	2015/12/01
9668671	Enhanced signal navigation and capture systems and methods	2017/06/06
9848898	Navigation and tissue capture systems and methods	2017/12/26
10154801	Enhanced signal navigation and capture systems and methods	2018/12/18

aegis medical innovations (4)

Number	Title	Issue Date
9144431	Enhanced signal navigation and capture systems and methods	2015/09/29
9668671	Enhanced signal navigation and capture systems and methods	2017/06/06
9848898	Navigation and tissue capture systems and methods	2017/12/26
10154801	Enhanced signal navigation and capture systems and methods	2018/12/18

AtriCure (4)

Number	Title	Issue Date
7828795	Surgical ablation and pacing device	2010/11/09
8034051	Ablation device with sensor	2011/10/11
8057471	Surgical ablation and pacing device	2011/11/15
8348939	Ablation device with sensor	2013/01/08

Biosense Webster (3)

Number	Title	Issue Date
7918850	Lesion assessment by pacing	2011/04/05
8357149	Filter for simultaneous pacing and ablation	2013/01/22
10792097	Ablation line contiguity index	2020/10/06

University Of Iowa Research Foundation (3)

Number	Title	Issue Date
9724170	Catheters, catheter systems, and methods for puncturing through a tissue structure and ablating a tissue region	2017/08/08
9861802	Catheters, catheter systems, and methods for puncturing through a tissue structure	2018/01/09
11426573	Catheters, catheter systems, and methods for puncturing through a tissue structure and ablating a tissue region	2022/08/30

MEDTRONIC ABLATION FRONTIERS TECHNOLOGIES, LLC (3)

Number	Title	Issue Date
8641704	Ablation therapy system and method for treating continuous atrial fibrillation	2014/02/04
8657814	User interface for tissue ablation system	2014/02/25
9005194	Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use	2015/04/14

Baxter International (2)

Number	Title	Issue Date
9445765	Internet-based system for characterizing patients undergoing an electrophysiology procedure	2016/09/20
9445765	Internet-based system for characterizing patients undergoing an electrophysiology procedure	2016/09/20

luxcath (2)

Number	Title	Issue Date
10076238	Systems and methods for visualizing ablated tissue	2018/09/18
10143517	Systems and methods for assessment of contact quality	2018/12/04

coral sand beach (2)

Number	Title	Issue Date
9226791	Systems for temperature-controlled ablation using radiometric feedback	2016/01/05
9277961	Systems and methods of radiometrically determining a hot-spot temperature of tissue being treated	2016/03/08

MEDTRONIC ALBATION FRONTIERS LLC (1)

Number	Title	Issue Date
9468495	Ablation catheter	2016/10/18

SIEMENS HEALTHCARE GMBH (1)

Number	Title	Issue Date
8422753	Method and system for automatic extraction of personalized left atrium models	2013/04/16

iowa approach (1)

Number	Title	Issue Date
10016232	Systems, devices, and methods for signal generation	2018/07/10

Colorado State University Research Foundation (1)

Number	Title	Issue Date
8512332	Real-time arc control in electrosurgical generators	2013/08/20

Tech Analysis

Class	Subclass	Type	Reference Factor	Citation Factor	Strength	Grant time	Early grant (%)
128	898	Emerging	Sustaining	Average	Medium	Average	68.7
606	32	Emerging	Average	Average	Medium	Average	58.5
606	34	Emerging	Average	Average	Medium	Average	51.1
606	41	Emerging	Average	Seminal	Medium High	Average	53.3
606	51	Emerging	Average	Seminal	Medium High	Average	52.0
607	101	Emerging	Average	Average	Medium	Average	60.8
607	105	Emerging	Average	Seminal	Medium High	Average	60.7